DLBCL occurs in lymphocytes, a type of white blood cell. These cells are an important part of your immune system and help defend your body from infection. When you have DLBCL, too many white blood cells that are affected by the disease build up in your lymph nodes, blood, and bone marrow. They may also build up in your spleen (an organ in your immune system) and cause swelling of this organ.
Everyone experiences diffuse large B-cell lymphoma, or DLBCL, differently. Because DLBCL is a fast-growing lymphoma, symptoms may show up sooner than in some others. It is important to pay attention to how your DLBCL may be affecting you. Tell your doctor if you notice any symptoms or changes in your health.
DLBCL can arise in lymph nodes or outside of the lymphatic system in the gastrointestinal tract, testes, thyroid, skin, breast, bone, or brain. Fast-growing lymphomas such as DLBCL usually require immediate treatment.
While you are being treated and after your treatment concludes, your doctor will continue to monitor your DLBCL.
RITUXAN HYCELA® (rituximab/hyaluronidase human) is a prescription medicine used to treat adults with:
You can only receive RITUXAN HYCELA after you receive at least 1 full dose of intravenous (IV) RITUXAN® (rituximab). Read the IV RITUXAN Medication Guide for more information about severe infusion reactions, which usually happen during the first dose with IV RITUXAN
RITUXAN HYCELA is not for use to treat medical conditions other than cancers
It is not known if RITUXAN HYCELA is safe and effective in children
RITUXAN HYCELA can cause serious side effects that can lead to death, including:
Skin reactions at or near the injection site (local), including injection site reactions can happen with RITUXAN HYCELA. Symptoms at or near the injection site may include: pain, swelling, hardness, redness, bleeding, itching, and rash. These reactions sometimes happen more than 24 hours after an injection of RITUXAN HYCELA
Tell your healthcare provider or get medical help right away if you get any of these symptoms during or after an injection of RITUXAN HYCELA: hives (red itchy welts) or rash; itching; swelling of your lips, tongue, throat, or face; sudden cough; shortness of breath, difficulty breathing, or wheezing; weakness; dizziness or feeling faint; palpitations (feeling like your heart is racing or fluttering); chest pain; fever; chills or shaking chills
RITUXAN HYCELA can cause serious side effects, including:
Your healthcare provider will stop treatment with RITUXAN HYCELA if you have severe, serious, or life-threatening side effects.
The most common side effects of RITUXAN HYCELA in people with:
Before receiving RITUXAN HYCELA, tell your healthcare provider about all of your medical conditions, including if you:
These are not all of the possible side effects with RITUXAN HYCELA. Call your doctor for medical advice about side effects. Please see the full Prescribing Information, including BOXED WARNINGS and Medication Guide, for additional Important Safety Information.
You may report side effects to the FDA at (800) FDA-1088 or www.fda.gov/medwatch. You may also report side effects to Genentech at (888) 835-2555.
The BrandX™ Co-pay Card Program may help lower the out-of-pocket costs for your patients.
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