Your first dose will always be RITUXAN® (rituximab) with CHOP chemotherapy or other anthracycline-based chemotherapy regimens. If you were able to receive and tolerate at least one full dose of RITUXAN, you may receive RITUXAN HYCELA™ (rituximab/hyaluronidase human) with CHOP chemotherapy or other anthracycline-based chemotherapy regimens during future cycles of treatment. The goal in using this combination of drugs is to keep your cancer from getting worse.

You will have up to 8 cycles, or rounds, of treatment. Each cycle will last 21 days. Treatment occurs on the first day of each cycle and is followed with time for rest and recovery.